Font Size: 

Magnitude of Helicobacter pylori infection and associated risk factors among HIV patients, Addis Ababa, Ethiopia; crossectional study

Getachew seid¹, kassu desta²,aster tsegaye²

^{1. Ethiopian public health institute}

^{2. Addis Ababa university college of health science}

Background

Helicobacter pylori is a spiral bacterium with flagella and a potent producer of urease. HIV-1 infected patients experience many form of opportunistic infections including gastro intestinal symptoms . The overall prevalence of H. pylori is suggested to be correlated with socioeconomic conditions. This study aims to assess the magnitude of H.pylori infection among HIV-patients and its correlation with hemoglobin level and associated risk factors for the prevalence of the infection.

Methods

A cros sectional study was conducted at yeka sub city which is located in north east of Addis Ababa. A cros sectional study was conducted to determine the prevalence of Helicobacter pylori based on stool antigen detection on HIV patient who were on ART follow up from January, 2017 to June, 2017.

Result

A total of 370, study participants were enrolled in this study, which 126(34.0%) were males and 244 (66.0%) females.  The mean (SD) age of the study subjects was 37(10.44) years with the range of 18 - 70 years. We did not register statistically significant differences regarding the level of education (p=.416), siblings (p=0.785), alcohol consumption(p=0.618), cigarette smoking and  lack of employment (p=0.673) between H.pylori positive and negative subjects. The mean Hemoglobin of the study participant was 11.6 g/dl. The mean Hemoglobin of H.pylori positive and negative subjects was 11.1 g/dl and 11.9 gm/dl respectively.

Conclusion

The overall stool antigen prevalence of H. pylori among HIV patients at yeka Health center was 31.6%. In our study we did not got any significant association between H.pylori and its risk factors like Cigarette smoking, WHO stage, alcohol drinking and others which needs further study.

Key words: HIV, Helicobacter pylori, Prevalence, Stool Antigen Test, Hemoglobin