EPHA Conference Systems, 31st EPHA Annual Conference

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Five year Survival of Cervical Cancer Patients and Predictors of Time to Death among Patients who Received Treatment at Tikur Anbesa Specialized Hospital, 2014-2019
benyam seifu woldeyes

Last modified: 2020-02-10

Abstract


Background: Cervical cancer (CC) is the 4th most common cancer among women worldwide. In Ethiopia, about 7,095 new CC cases are diagnosed annually and it is the second leading cause of cancer death among females. There is limited evidence on survival status and predictors of time to death among CC patients in Ethiopia. Thus, the finding of the study could contribute to address filling the information gap.

Objective: To assess survival status and identify predictors of time to death among CC patients admitted at Tikur Anbesa specialized Hospital.

Methods: Facility based retrospective cohort study was conducted at Tikur Anbesa specialized Hospital a sample of 348 patients under follow-up time from June 2014 to June 2019. Systematic random sampling technique was used to select study participants. Data was extracted from patient card and the current survival status was identified through phone call using phone number recorded on the patient card. The data was collected and entered using CSEntry for android version and exported to SPSS version 23 for analysis. Kaplan Meier method was used to estimate survival functions and Cox-proportional hazard regression analysis used to identify independent predictors of time to death.

 

Results: The cumulative survival probability of CC patient’s was 62%, 36% and 35 % at 1, 3 and 5 years of follow up respectively. The median (IQR) follow-up time of the entire cohorts was 18.55 (8.96-49.65) months. The independent predictors of time to death were: age older than 50 years [AHR: 1.4 (95% CI: 1.1-1.9)], late stage of CC at diagnosis [AHR: 2.2 (95% CI: 1.7-2.9)], didn’t receive CC treatment [AHR: 2.1 (95% CI: 1.5-3.1)] and HIV positive [AHR: 2.3 (95% CI: 1.4-3.8)].

Conclusion and recommendation: The death rate of CC patients was 30.22 per 100 person-years of follow up. In order to improve a patient’s chance of surviving CC, the government and other concerned stakeholders should mobilize resources to create awareness about CC, its early signs and symptoms and need to engage in different approaches that could improve women’s health care seeking behavior. Also, routine CC screening programs should be strengthen for high risk women such as elderly and HIV positive women.

 

Key word: Cervical cancer, survival, stage of cancer, Predictors of time to death, TASH, Ethiopia.