EPHA Conference Systems, 31st EPHA Annual Conference

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Survival Status and Associated Factors of Death Among Cervical Cancer Patients Attending Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia,2019.A retrospective cohort study
Mulugeta Wassie Alamirew

Last modified: 2020-02-25

Abstract


Abstract

Introduction: Cervical cancer is a cancer of uterine cervix caused mostly by sexually-acquired infection called Human papillomavirus (HPV. In developing countries, less than 50% of women with cervical cancer survive longer than 5 years. Therefore, the objective of this study was to asses survival status and associated factors of death among cervical cancer patients attending at Tikur Anbesa Specialized Hospital (TASH), Ethiopia.

Methods and materials: Institutional based retrospective cohort study was conducted from March to April 2019 at Tikur Anbesa Specialized Hospital oncology center. Data was collected from patient’s chart using pre-tested and structured checklist prepared in English and analyzed using STATA14.2. Cox regression model was used to identify Variables that affected survival.

Result: The overall survival rate was 38.62% at five years. There were a significance differences in survival experience between categories of stage of cervical cancer, age of patients, comorbidity, substance use, base line anemia and treatment modalities. Being stage IV [AHR = 11.76; 95% CI (4.02-34.4)] ,being advanced age [AHR = 5.99; 95% CI (2.1-17.08)], being comorbid[AHR=1.58; 95%CI(1.14-2.19)], using substance[AHR=1.56;95% CI(1.09-2.22)] and being anemic [AHR=1.6;95% CI(1.11-2.36)] increased the risk of death.

Conclusion: The overall survival rate was lower than high- and middle-income countries and Significant factors of death after diagnosis of cervical cancer were; advanced FIGO stage, base line anemia, comorbidity, substance use, advanced age and treatment modality.

Recommendations: Better to expand cervical cancer early screening programs and treatment facilities and strengthen awareness in collaboration with public medias about cervical cancer prevention, screening and treatment options.